Welcome to the VIVIBRAIN project website. This page is currently under construction. Soon, it will provide you with information about the project and its progress.

Here is the executive summary of the project that was recently funded by the Community of Madrid, Spain (2019-2022):

“This project, VIVIBRAIN, aims to measure neuronal connectivity directly using magnetoencephalography (MEG) in a cohort of 100 adults (2 age groups of 50 participants:  70 – 75, 75 – 80) randomly allocated to Vivifrail exercise program (intervention) or general health recommendations incl. physical activity (control) longitudinally over time to detect physical and cognitive decline, their neural correlates, and the influence of genetic propensity to type 2 diabetes and obesity on the effectiveness of the physical activity intervention. This is the first study that aims to validate the EU-promoted “Vivifrail” ( intervention and tries to elucidate its associated impact on brain health.

The objectives of this project are:

  1. Evaluate the effectiveness of the Vivifrail excercise intervention in slowing functional and cognitive decline.
  2. Describe the effectiveness of the Vivifrail excercise intervention on neural connectivity in the aging brain.
  3. Validate and contrast the effects of exercise, type 2 diabetes, and obesity on physical and cognitive decline and contrast if they express differentially according to different in location and intensity of brain health measures.

The VIVIBRAIN proposal is aligned with the H2020 Society Challenge <<Health, Demographic Change and Wellbeing>> objectives, as well as the objectives identified in the 2013­2020 Spanish RTD Strategy under the same label, by improving our understanding of the causes and mechanisms underlying health, healthy ageing and disease.”